Can I sin so as to “lose my salvation”?

"If as a Christian I can sin so as to "lose my salvation," just what sin or sins will place me in such danger?"

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“I have some questions about your last video. Concerning the Holy Spirit being a seal of our salvation, if one sins, is that seal broken? Does the Holy Spirit come back if one repents? I don't understand. That makes me insecure if the HS leaves every time I sin.”

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